\n \nComposition?: \n \nFamicef??250 Tablet : Cefuroxime Axetil USP 250 mg. \n \nFamicef??500 Tablet : Cefuroxime Axetil USP 500 mg. \n \nFamicef??Powder for Suspension : Cefuroxime Axetil USP 125 mg /5 ml. \n \nFamicef??750 mg IM / IV Injection : Cefuroxime Sodium USP sterile powder equivalent to Cefuroxime 750 mg / vial. \n \nFamicef??1.5 g IV injection : Cefuroxime Sodium USP sterile powder equivalent to Cefuroxime 1.5 g / vial. \n \n  \n \nIndications?: \n \n? Upper respiratory tract infections: Ear, nose and throat infections such as otitis media, sinusitis, tonsillitis and pharyngitis \n \n?Lower respiratory tract infection : Acute bronchitis, acute exacerbations of chronic bronchitis and pneumonia \n \n?Skin and soft tissue infections : Furunculosis, pyoderma and impetigo \n \n? Genito-urinary tract infections: Pyelonephritis, urethritis and cystitis \n \n? Multi drug resistant typhoid fever \n \n? Gonorrhoea : Acute uncomplicated gonococcal urethritis and cervicitis \n \n?Early Lyme Disease and subsequent prevention of late Lyme Disease. \n \n  \n \nDosage & Administration?: \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n

Infection		Dosage		Duration
Adolescents and Adults (13 years and older)
Pharyngitis / tonsillitis		250 mg b.i.d.		10 days
Acute bacterial maxillary sinusitis		250 mg b.i.d.		10 days
Acute bacterial exacerbations of chronic bronchitis		250 or 500 mg b.i.d.		10 days
Secondary bacterial infections of acute bronchitis		250 or 500 mg b.i.d.		5 - 10 days
Uncomplicated skin and skin-structure infections		250 or 500 mg b.i.d.		10 days
Uncomplicated urinary tract infections		125 or 250 mg b.i.d.		7 - 10 days
Uncomplicated gonorrhoea		1,000 mg once		Single dose
Early Lyme Disease		500 mg b.i.d		20 days
Pediatric Patients (who can swallow tablets whole)
Acute otitis media		250 mg b.i.d.		10 days
Acute bacterial maxillary sinusitis		250 mg b.i.d.		10 days
Infection	Dosage (divided b.i.d.)		Maximum Dose		Duration
Pediatric Patients (3 months to 12 years)
Pharyngitis / tonsillitis	20 mg/kg/day		500 mg		10 days
Acute otitis media	30 mg/kg/day		1,000 mg		10 days
Acute bacterial maxillary sinusitis	30 mg/kg/day		1,000 mg		10 days
Impetigo	30 mg/kg/day		1,000 mg		10 days

\nInjection : Adult : 750 mg three times daily by IM / IV injection. \n \nInfants and Children : 30 - 100 mg / kg /day given in 3 or 4 equally divided doses. A dose of 60 mg / kg /day is appropriate for most infections. \n \nNeonate : 30 - 100 mg / kg / day given in 2 or 3 equally divided doses. \n \nSurgical prophylaxis : 1.5 gm by IV injection at induction of anaesthesia. Thereafter, give 750 mg IM / IV every 8 hours when the procedure is prolonged. \n \nSequential therapy in adults : Pneumonia : 1.5 gm IV injection three times or twice daily for 2 - 3 days, followed by 500 mg twice daily (oral) for 7 - 10 days. Acute exacerbation's of chronic bronchitis : 750 mg three times or twice daily (IM / IV injection) for 2 - 3 days, followed by 500 mg twice daily (oral) for 5 - 10 days. (Duration of both parenteral and oral therapy is determined by the severity of the infections and the clinical status of the patient). \n \nOther recommendations : In Gonorrhoea : Adults : 1.5 gm as a single dose (as 2 X 750 mg injections given intramuscularly with different sites, e.g. each buttock). In Meningitis : Adults : 3 gm IV injection three times daily. \n \nChildren (above 3 months of age) : 200 - 240 mg / kg /day by IV injection in 3 or 4 divided doses reduced to 100 mg / kg / day after 3 days or on clinical improvement. \n \nNeonates : 100 mg / kg / day by IV injection reduced to 50 mg / kg / day. \n \nIn bone and joint infections : Adults : 1.5 gm injection 3 times daily. \n \nChildren (above 3 months of age) : 150 mg / kg / day (not to exceed the maximum adult dose) in equally divided doses every 8 hours. \n \n