Indication:? \nMaxcef^TM?(Cefotaxime) is indicated for the treatment of the following infections when caused by bacteria of established sensitivity: Septicaemia, Respiratory Tract Infections, Urinary Tract Infections, Soft-tissue Infection, Bone & Joint Infections, Obstetric & gynaecological infections, Gonorrhoea particularly when penicillin has failed or is unsuitable, Other Bacterial Infections such as meningitis. Prophylaxis: The administration of Cefotaxime prophylactically may reduce the incidence of certain post-operative infections in patients undergoing surgical procedures that are classified as contaminated or potentially contaminated or in clean operation where infection would have serious effects.

Dosage & Administration: \nAdults: \nThe recommended dosage for mild to moderate infections is 1 gm 12 hourly. In severe infections dosage may be increased up to 12 gm daily given in 3 or 4 divided doses. For infections caused by sensitive Pseudomonas spp. daily doses of greater than 6 gm will usually be required. \nChildren: \nThe usual dosage range is 100-150 mg/kg/day in 2 to 4 divided doses. However, in severe infections doses of up to 200 mg/kg/day may be required. \nNeonates: \nThe recommended dosage is 50 mg/kg/day in 2 to 4 divided doses. In severe infections 150-200 mg/kg /day, in divided doses, can be given.

Preparation:? \nMaxcef^TM?250 IM/IV injection: Pack of 1 vial contains Cefotaxime 250 mg accompanied by a solvent ampoule of 5 ml water for injection. It also contains a complementary pouch comprised of disposable syringe (5 ml), alcohol pad and first aid bandage. \nMaxcef^TM 500 mg IM/IV injection: Pack of 1 vial contains Cefotaxime 500 mg accompanied by a solvent ampoule of 10 ml water for injection. It also contains a complementary pouch comprised of disposable syringe (10 ml), alcohol pad and first aid bandage.