Fluconazole is a member of the triazole class of antifungal agent,
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Indications:
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Vaginal candidiasis, Cryptococcal meningitis, C.opharyngeal, and esophageal candidiasis & Onychomycosis etc.
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Mode of Action:?
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Fluconazole inhibits the fungal cytochrome P450 enzyme 14cr-demethylase that inhibits the biosynthesis of ergosterol in fungi and changes the composition of other lipid components in the membrane, resulting in fungal cell necrosis.