Tablet Cardopril 25
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\nTablet Cardopril 25\n | \n
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| What is and what it is used for? | \n
| Cardopril (Captopril) is the first of a new class of antihypertensive agents a highly specific inhibitor of angiotensin converting enzyme. It is also effective in the management of heart failure. Cardopril is designated chemically as (1-[(2S)-3 Mercapto-2 methyl propionyl-L-proline.) Cardopril is available in potencies of 25 mg & 50 mg as scored tablet for oral administration. Cardopril inhibits angiotenin converting enzyme (ACE) involved in the conversion of angiotensin I to angiotensin II and may also reduce the degradation of bradykinin. Cardopril produces a reduction in total peripheral resistance and in patients with congestive heart failure & reduction in both preload and post load. Following oral administration, Cardopril produces a maximal effect within 1 to 2 hours, although the full effect may not develop for several weeks during chronic dosing. The duration of action is dose dependent and may persist for 6 to 12 hours. | \n
| Cardopril is used for mild to moderate hypertension as an adjunct to thiazide therapy in patients who have not responded effectively to thiazide treatment alone. Severe hypertension where standard therapy has failed. Cardopril is effective alone and in combination with other antihypertensive agents especially thiazide type diuretics. The blood pressure lowering effect of Cardopril and thiazides are approximately additive. It is also used as an adjunct to the treatment of severe congestive heart failure. | \n
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