Description:

Amlodipine is a Calcium Channel Blocker & Olmesartan is Angiotensin Receptor Blocker.

Indications:

Stage-II Hypertension.

Amlodipine blocks vascular smooth muscle calcium channel thus reducing arterial contraction and Olmesartan block AT- 1 receptors thus reducing peripheral resistance , aldosterone synthesis and vasopressin release and finally reduced high Blood Pressure