Gentamicin is a bactericidal antibiotic of Aminoglycoside class and is used against a wide range of infections. It is available in the form of injection and cream.
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Indications:
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Injection: Sepsis with gram-negative bacteria, pelvic inflammatory disease, urinary tract infections, pre- and post-surgical prophylaxis, peritonitis, bacterial meningitis, infected burn, septic abortion, cellulitis, bacterial endocarditis, etc.
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Mode of Action:?
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Gentamicin acts by irreversible inhibition of protein synthesis by binding to the 30s subunit of bacterial ribosome. As a result the bacteria grow without any functional protein and ultimately are killed.