Indication

Irritable bowel syndrome, GI tract spasm

Adult Dose

Oral Irritable bowel syndrome; Gastrointestinal tract spasm Adult: Peppermint oil: 0.2 ml tid, increased to 0.4 ml tid if necessary, for up to 3 mth.

Contraindication

Pregnancy; cholecystitis; hepatic damage; children.

Mode of Action

The main constituents of peppermint oil are menthol (29%-48%), menthone (20%-31%) and methyl acetate (3%-10%). It relieves flatulence and colic by relaxation of GI tract smooth muscles.

Precaution

Hiatal hernia, Pregnancy, lactation.

Side Effect

Irritation; erythematous skin rash; headache; bradycardia; muscle tremors and ataxia; heartburn; exacerbation of asthma with wheezing and dypnoea; contact dermatitis, urticaria.

Interaction

Exacerbation of adverse effects if taken with alcohol; enteric-coated preparations containing peppermint oil should not be taken immediately with antacids.