Online Medicine

Tablet Twinvir - 90+400 mg (6's pack)

6,000

Quantity: 1

Product Warranty

Payment Methods

payment-logo

About the Product

Full Description

\n
\n
\n
\n
\n
\n

Presentation

\nTwinvir: Each tablet contains Ledipasvir INN 90 mg and Sofosbuvir INN 400 mg \n \n
\n
\n

Description

\nIt is a fixed-dose combination tablet containing Ledipasvir and Sofosbuvir for oral administration. Ledipasvir is an HCV NS5A inhibitor and Sofosbuvir is a nucleotide analog inhibitor of HCV NS5B polymerase. \n \n
\n
\n

Indications

\nLedipasvir and Sofosbuvir combination is indicated for the treatment of chronic hepatitis C (CHC) genotype 1, 4 & 6 infection in adults. \n \n
\n
\n

Dosage & Administration

\n? Recommended dosage: One tablet (90 mg of Ledipasvir and 400 mg of Sofosbuvir) taken orally once daily with or without food \n? Recommended treatment duration: \nTreatment-na?ve with or without cirrhosis: 12 weeks \n? Treatment-experienced without cirrhosis: 12 weeks \n? Treatment-experienced with cirrhosis: 24 weeks \nA dose recommendation cannot be made for patients with severe renal impairment or end stage renal disease. \n \n
\n
\n

Side Effects

\nThe most common adverse reactions with treatment with Ledipasvir and Sofosbuvir combination for 8, 12, or 24 weeks are fatigue and headache. \n \n
\n
\n

Precautions

\n? Bradycardia with Amiodarone coadministration: Serious symptomatic bradycardia may occur in patients taking Amiodarone, particularly in patients also receiving beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease. Coadministration of Amiodarone with Ledipasvir and Sofosbuvir combination is not recommended. In patients without viable treatment options, cardiac monitoring is recommended \n? Use with other drugs containing sofosbuvir, is not recommended \n \n
\n
\n

Use in Pregnancy & Lactation

\nPregnancy Category B \nThere are no adequate and well-controlled studies with Ledipasvir and Sofosbuvir combination in pregnant women. \nLedipasvir and Sofosbuvir combination should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. \nIt is not known whether Ledipasvir and Sofosbuvir combination and its metabolites are present in human breast milk. \n \nWell, the A-line prom dresses are certainly suitable for all women. It is a kind of neutral dress which is compatible for brides with all kinds of body shape such as big bottom or pear, apple, hourglass and even petite. Following the latest trend of bridal gown, strapless?prom dresses ukare very famous among women. Basically, the strapless wedding dress involves sweetheart neckline cut to prettier the dress. \n \nPediatric Use \nSafety and effectiveness of Ledipasvir and Sofosbuvir combination have not been established in pediatric patients \n \n
\n
\n

Drug Interaction

\n? Coadministration with amiodarone may result in serious symptomatic bradycardia. Use of Ledipasvir and Sofosbuvir combination with Amiodarone is not recommended \n? P-gp inducers (e.g., Rifampin, St. John?s wort): May alter concentrations of Ledipasvir and Sofosbuvir. Use of Ledipasvir and Sofosbuvir combination with P-gp inducers is not recommended \n \n
\n
\n

Commercial Pack

\nTwinvir Container Pack: Each bottles contains 28 tablets. \nTwinvir Blister pack: Each box contains 1 blister strip of 6 tablets. \n \n
\n
\n
\n
\n
\n

Reviews:


No Review



Cart

0 Items

0
Cart 0 Item
close
close

Your purchase will delivered in 1 shipment

Express delivery
Empty

Your shopping bag is empty. Start shopping now.