Indomethacin is an NSAID having properties of antipyretic and analgesic effects. A great number of pharmacological studies have proved that Indomethacin has strong anti-inflammatory, analgesic, and antipyretic properties. Unlike the corticosteriods, the effect of Indomethacin is not related to the pituitary gland or the adrenals.
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Presentation:
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Reumacap Capsule: Each capsule contains Indomethacin BP 25 mg. Reumacap SR Capsule: Each sustained release capsule contains Indomethacin BP 75 mg.
By mouth, rheumatic disease, 50-200 mg daily in divided doses, with food. Acute gout, 150-200 mg daily in divided doses. Dismenorrhea, upto 75 mg daily. Children: Not recommended
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Contrainidications:
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Indomethacin is contraindicated in patients with ulcer, gastritis, active ulcerative colitis, and should be used with caution in patients with a history of these disorders. It is also contraindicated in previously hypersensitive patient.
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Side effects:
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Headaches, usually in the morning and mild vertigo may occur during the early weeks of therapy. These symptoms are transient and usually disappear with continued use or by reduction of the dose. Gastrointestinal reactions such as nausea, vomiting, diarrhoea, epigastric and abdominal pain are often due to large doses of the drug and disappear when the dose is reduced.
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Drug interaction:
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It may interact with anticoagulants, lithium, diuretics, antihypertensive drugs, diflunisal and sulfonylureas.
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Use in special groups:
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Use in Pregnancy: It is not recommended for pregnant women, because at the present time clinical studies are insufficient. Indomethacin is not given normally in neonates except when used to assist closure of a patent ductus arteriosus.
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Packing:
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Reumacap Capsule : Each box contains 100's capsules in blister pack. Reumacap SR Capsule: Each box contains 100's capsules in blister pack.