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\n \nComposition : \n \nTablet 200 : Metronidazole BP 200 mg. \n \nTablet 400 : Metronidazole BP 400 mg. \n \nSuspension : Metronidazole 200 mg / 5 ml. \n \nSuppository : Metronidazole BP 500 mg. \n \nIV Infusion : Metronidazole BP 500 mg / 100 ml (5 mg /ml). \n \n  \n \nIndication : \n \nAmebiasis, urogenital trichomoniasis (both symptomatic and asymptomatic), giardiasis, anaerobic infections, acute ulcerative gingivitis, intra-abdominal infections (peritonitis, intra-abdominal abscess and liver abscess), skin infections, gynaecological infections (endometritis, endomyometritis, tubo-ovarian abscess and post-surgical vaginal cuff infection), bacterial septicaemia, bone and joint infections, CNS infections (meningitis and brain abscess), lower respiratory tract infections (pneumonia, empyema and lung abscess), endocarditis, leg ulcer and pressure sores, prophylaxis of colorectal and pelvic surgery and eradication of Helicobacter pylori in triple therapy with Amoxycillin and Ranitidine. \n \n  \n \nDosage & Administration :?For Tablets and Suspension : \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n
IndicationsDuration of treatment in daysAdults and Children over 10 YearsChildren
7-10 years3-7 years1-3 years
Invasive intestinal amebiasis5-10800 mg thrice daily400 mg thrice daily200 mg four times daily200 mg thrice daily
Asymptomatic amebiasis5-10400-800 mg thrice daily200-400 mg thrice daily100-200 mg four times daily100-200 mg thrice daily
Hepatic and extra intestinal Amebic dysentery5-10400-800 mg thrice daily200-400 mg thrice daily100-200 mg four times daily100-200 mg thrice daily
Giardiasis32 g once daily1 g once daily600-800 mg once daily500 mg once daily
Trichomoniasis (both the consorts should be treated simultaneously)7200 mg thrice daily \nor 400 mg twice daily100 mg thrice daily100 mg thrice daily50 mg thrice daily
2800 mg in the morning and 1.2 g at night
1Single dose of 2 g
Bacterial vaginosis7400 mg twice daily
1Single dose of 2 g
Acute ulcerative gingivitis3-7200 mg thrice daily100 mg thrice daily100 mg twice daily50 mg thrice daily
Leg ulcer and pressure sores7400 mg thrice daily
Acute dental infections3-7200 mg thrice daily
Anaerobic infections7800 mg thrice daily and then 400 mg thrice daily7.5 mg/kg body weight thrice daily.
\nFor suppository : Anaerobic Infections : Adults : 1 g every 8 hours for 3 days, then 1 g every 12 hours. \n \nChildren (5 - 10 years) : 500 mg every 8 hours for 3 days, then every 12 hours, Over 10 years adult dose. \n \nSurgical Prophylaxis : Adults : 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures. \n \nChildren (5 - 10 years) : 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high risk procedures. \n \nFor IV Infusion : Adults and children over 12 years : Infuse 500 mg 8 hourly at a rate of 5ml /minute and a maximum of 4 g should not be exceeded during a 24-hour period. For surgical prophylaxis, administration shortly before surgery should be followed by 8-hourly doses for the next 24 hours. \n \nChildren under 12 years : 7.5mg / kg body weight /day every 8 hours at a rate of 5ml / minute. \n \nTriple therapy against H. pylori infection (gastritis, peptic ulcers and gastric cancer) : Two weeks regimen : Dirozyl??(Metronidazole) 500 mg thrice daily plus Moxilin (Amoxycillin) 750 mg thrice daily plus Ranidin (Ranitidine) 300 mg at night or 150 mg twice daily. \n \n

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