\n \nThe daily dose of DIFLU should be based on the nature and severity of the fungal infection. Most cases of the fungal infections require multiple dose therapy. Treatment should be continued until clinical parameters of laboratory tests indicate that active fungal infection has subsided. An inadequate period of treatment may lead to recurrence of active infection. Immunocompromised patients usually require maintenance therapy to prevent relapse. \n
\n \n \nInfections | \nRecommended dosage | \n
\n \nAdults: \nVaginal candidiasis | \n150 mg as a single dose | \n
\n \nOropharyngeal candidiasis | \n200 mg on the 1st day followed by 100 mg dailly for 14 days | \n
\n \nOesophageal candidiasis | \n200 mg on the 1st day followed by 100 mg dailly for 14-30 days | \n
\n \nSystemic candidiasis & Cryptococcal infection | \n400 mg on the 1st day followed by 200 mg daily for 28 days or longer based on clinical response | \n
\n \nTinea corporis/ tinea cruris/ tinea pedis/ other tinea kerion | \n50 mg daily for 2-4 weeks (for up to 6 weeks in tinea pedis) | \n
\n \nPrevention of fungal infections in immunocompromised patients | \n50-400 mg daily adjusted according to risk | \n
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\n \n \nNeonates : | \n? | \n
\n \nOesophageal candidiasis | \n3 mg/Kg every 72 hours up to 2 weeks old \n3 mg/Kg every 48 hours up to 2-4 weeks old | \n
\n \nSystemic candidiasis & cryptococcal infection | \n6-12 mg/kg every 72 hours up to 2 weeks old \n6-12 mg/kg every 48 hours up to 2-4 weeks old | \n
\n \nPrevention of fungal infections in immunocompromised patients | \n3-12 mg/kg every 72 hours up to 2 weeks old \n3-12 mg/kg every 48 hours up to 2-4 weeks old | \n
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