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Eye Drops Polyforte (.35+.124+.5 mg)

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About the Product

Full Description

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Tamsulosin is a selective alpha-1 adrenoreceptor antagonist. Tamsulosin binds selectively and competitively to postsynaptic alpha-1 adrenoceptors, in particular to subtypes alpha1A and alpha1D. It relieves obstruction by relaxing smooth muscle in prostate and urethra. Thus it increases the maximum urinary flow rate.
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Prostanil MR capsule: Each capsule contains Tamsulosin Hydrochloride BP 0.4 mg as modified release pellets.
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Prostanil MR is indicated for the treatment of the signs and symptoms of Benign Prostattic Hyperplasia(BPH).
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The recommended dose is 0.4 mg once daily. It should be taken after breakfast or the first meal of the day. If necessary, the dose may be increased to 0.8 mg once daily after 2-4 weeks. If administration is discontinued or interrupted for several days at either the 0.4 mg or 0.8 mg dose, therapy should be started again with the 0.4 mg once daily dose.
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It is contraindicated in patients known to be hypersensitive to Tamsulosin Hydrochloride or any component of the product, a history of orthostatic hypotension and severe hepatic insufficiency.
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Dizziness, less frequently headache, asthenia, postural hypotension and palpitations, and abnormal ejaculation is an uncommon side effect. Precautions: As with other alpha-1 adrenoceptor antagonist, a reduction in blood pressure can occur in individual cases during treatment with Tamsulosin, as a result of which, rarely syncope can occur. The treatment of severely renal impaired patients ( creatinine clearance below 10 ml/min) should be approached with caution, as these patients have not been studied.
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Concomitant treatment with Ketoconazole, Cimetidine and Paroxetine bring about a rise in plasma levels of Tamsulosin, and Frusemide a fall, but as levels remain within the normal range dosage schedule does not need to be changed. Interaction may be expected with alpha-adrenoreceptor antagonists. Diclofenac & warfarin, however, may increase the elimination rate of Tamsulosin.
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Use in pregnancy and lactation: It is not indicated for use in women. Use in children: It is not indicated for use in pediatric.
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Prostanil MR capsule: Each box containing 30's capsule in blister pack.
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