Gynoxin is a combined preparation of Neomycin, Polymyxin B, Nystatin and Metronidazole. Neomycin is an aminoglycoside having bactericidal activity against both gram-positive and gram-negative bacteria. Polymyxin B is effective against gram-negative bacteria including Pseudomonas aeruginosa. Nystatin is a polyene antifungal agent with excellent antifungal activity. Metronidazole is a nitroimidazole which is effective against various anaerobic bacteria and protozoa.