Alcaftadine is an H1 histamine receptor antagonist and inhibitor of the release of histamine from mast cells. In addition it antagonizes H2 & H4 receptors and thus provides antihistaminic actions. It also decreases chemotaxis and inhibits the activation of eosinophil.
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Presentation:
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Caftadin Sterile Ophthalmic Solution: Each ml contains Alcaftadine INN 2.5 mg. Preservative: Sodium Perborate BP 0.01%.
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Pharmacology:
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Alcaftadine is an H1 histamine receptor antagonist and inhibitor of the release of histamine from mast cells. In addition, it antagonizes H2 & H4 receptors and thus provides antihistaminic actions. It also decreases chemotaxis and inhibits the activation of eosinophil.
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Indication:
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Caftadin Sterile Ophthalmic Solution is indicated for the treatment of signs and symptoms of allergic conditions of the anterior segment of the eye.
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Dosage & Administration:
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Instill 1 drop in the affected eye(s) once daily.
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Contrainidications:
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None.
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Warning & Precautions:
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For ophthalmic use only. Patients should be advised not to wear contact lenses if their eye is red.
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Side effects:
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Most frequently reported side effects are mild eye irritation, burning or stinging upon instillation and redness.
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Use in special groups:
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Use in pregnancy: Pregnancy category B. Use in lactation: It is not known whether Alcaftadine is excreted in human milk. Caution should be exercised when Alcaftadine is administered to a nursing mother. Use in children: Safety and effectiveness in children below the age of 2 years have not been established. Use in elderly patients: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.
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Packing:
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Caftadin Sterile Ophthalmic Solution: Each plastic dropper bottle contains 5 ml sterile ophthalmic solution.