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Neugalin 50 mg Capsule - 10's strip

110

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SKU: T2M0997

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Neugalin \n(Pregabalin INN) Capsule \n \nDescription \nPregabalin is a structural derivative of the inhibitory neurotransmitter gamma aminobutyric acid (GABA), it does \nnot bind directly to GABAA, GABAB and benzodiazepine receptor. Pregabalin selectively binds to the alpha2delta subunit protein of voltage-gated calcium channels in various regions of central nervous system tissues. \nPregabalin oral bioavailability is approximately 90% and it is well absorbed after oral administration. \n \nComposition \nNeugalin 25 : Each capsule contains Pregabalin INN 25 mg. \nNeugalin 50 : Each capsule contains Pregabalin INN 50 mg. \nNeugalin 75 : Each capsule contains Pregabalin INN 75 mg. \n \nIndications \n? Neuropathic pain from diabetic neuropathy. \n? Post herpetic neuralgia. \n? Fibromyalgia. \n? Adjunctive therapy in adults with partial seizures with or without secondary generalization. \n? Generalized anxiety disorder. \n \nDosage and Administration \nNeuropathic pain \nInitially 150 mg/day in 2-3 divided doses, may be increased if necessary after 3-7 days to 300 mg daily in 2 \ndivided doses, The dose may be increased further if necessary after 7 days to maximum 600 mg daily in two \ndivided doses . \n \nPost herpetic neuralgia \nThe recommended dose is 75 to 150 mg two times a day, dosing should begin at 75 mg two times a day and \nmay be increased to 300 mg/day within 1 week based on efficacy and tolerability. \n \nFibromyalgia \nThe recommended dose of Pregabalin for fibromyalgia is 300 to 450 mg/day in two divided doses. \n \nEpilepsy \nInitially 150 mg daily in 2 divided doses, increased if necessary after 7 days to 300 mg daily in 2 divided doses, \nincreased further if necessary after 7 days to maximum 600 mg daily in 2 divided doses. \nGeneralized anxiety disorder \nInitially 150 mg daily in 2 divided doses, increased if necessary after 7 days to 300 mg in 2 divided doses, \nincreased further if necessary after 7 days to maximum 600 mg daily in 2 divided doses. \nOr as directed by the physician. \n \nContraindications \nPregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components. \n \nSide effects \nThe most common side effects reported are tiredness, dizziness, headache, dry mouth, nausea, vomiting, \nconstipation. \n \nPrecautions \nAbrupt or rapid discontinuation may result in insomnia, nausea, headache, or diarrhea. Concomitant treatment \nwith Pregabalin and a antidiabetic agent may lead to an additive effect on edema and weight gain. For patients \nwith preexisting cardiac conditions, this may increase the risk of heart failure. \nUse in pregnancy and lactation \nPregnancy category C. It should be used during pregnancy only if the potential benefits justifies the potential \nrisk to the fetus. Breast feeding is not recommended during treatment with Pregabalin. \n \nPediatric use \nThe safety and efficacy of pregabalin in pediatric patients have not been established. \n \nDrug interactions \nInteractions may occur with opioids benzodiazepines, barbiturates, ethanol (alcohol), and other drugs that \ndepress the central nervous system. \n \nOverdosage \nOverdose of up to 8000 mg has been reported. The most commonly reported adverse events in overdose are \nsomnolence, confusional state, agitation and restlessness. \n \nSupply \nNeugalin 25 : Each box contains 3 x 10 capsules in Alu-Alu blisters. \nNeugalin 50 : Each box contains 3 x 10 capsules in Alu-Alu blisters. \nNeugalin 75 : Each box contains 3 x 10 capsules in Alu-Alu blisters. \nKeep all medicines out of reach of children. \nStore in a cool and dry place, protected from light. \n \nFurther information is available on request. \nlab \nFOR HEALTH, VIGOUR AND HAPPINESS \nDHAMRAI, DHAKA, BANGLADESH \n07 1286/02

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