\n \nComposition : \n \nTablet 200 : Metronidazole BP 200 mg. \n \nTablet 400 : Metronidazole BP 400 mg. \n \nSuspension : Metronidazole 200 mg / 5 ml. \n \nSuppository : Metronidazole BP 500 mg. \n \nIV Infusion : Metronidazole BP 500 mg / 100 ml (5 mg /ml). \n \n  \n \nIndication : \n \nAmebiasis, urogenital trichomoniasis (both symptomatic and asymptomatic), giardiasis, anaerobic infections, acute ulcerative gingivitis, intra-abdominal infections (peritonitis, intra-abdominal abscess and liver abscess), skin infections, gynaecological infections (endometritis, endomyometritis, tubo-ovarian abscess and post-surgical vaginal cuff infection), bacterial septicaemia, bone and joint infections, CNS infections (meningitis and brain abscess), lower respiratory tract infections (pneumonia, empyema and lung abscess), endocarditis, leg ulcer and pressure sores, prophylaxis of colorectal and pelvic surgery and eradication of Helicobacter pylori in triple therapy with Amoxycillin and Ranitidine. \n \n  \n \nDosage & Administration :?For Tablets and Suspension : \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n

Indications	Duration of treatment in days	Adults and Children over 10 Years	Children
			7-10 years	3-7 years	1-3 years
Invasive intestinal amebiasis	5-10	800 mg thrice daily	400 mg thrice daily	200 mg four times daily	200 mg thrice daily
Asymptomatic amebiasis	5-10	400-800 mg thrice daily	200-400 mg thrice daily	100-200 mg four times daily	100-200 mg thrice daily
Hepatic and extra intestinal Amebic dysentery	5-10	400-800 mg thrice daily	200-400 mg thrice daily	100-200 mg four times daily	100-200 mg thrice daily
Giardiasis	3	2 g once daily	1 g once daily	600-800 mg once daily	500 mg once daily
Trichomoniasis (both the consorts should be treated simultaneously)	7	200 mg thrice daily \nor 400 mg twice daily	100 mg thrice daily	100 mg thrice daily	50 mg thrice daily
	2	800 mg in the morning and 1.2 g at night
	1	Single dose of 2 g
Bacterial vaginosis	7	400 mg twice daily
	1	Single dose of 2 g
Acute ulcerative gingivitis	3-7	200 mg thrice daily	100 mg thrice daily	100 mg twice daily	50 mg thrice daily
Leg ulcer and pressure sores	7	400 mg thrice daily
Acute dental infections	3-7	200 mg thrice daily
Anaerobic infections	7	800 mg thrice daily and then 400 mg thrice daily	7.5 mg/kg body weight thrice daily.

\nFor suppository : Anaerobic Infections : Adults : 1 g every 8 hours for 3 days, then 1 g every 12 hours. \n \nChildren (5 - 10 years) : 500 mg every 8 hours for 3 days, then every 12 hours, Over 10 years adult dose. \n \nSurgical Prophylaxis : Adults : 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures. \n \nChildren (5 - 10 years) : 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high risk procedures. \n \nFor IV Infusion : Adults and children over 12 years : Infuse 500 mg 8 hourly at a rate of 5ml /minute and a maximum of 4 g should not be exceeded during a 24-hour period. For surgical prophylaxis, administration shortly before surgery should be followed by 8-hourly doses for the next 24 hours. \n \nChildren under 12 years : 7.5mg / kg body weight /day every 8 hours at a rate of 5ml / minute. \n \nTriple therapy against H. pylori infection (gastritis, peptic ulcers and gastric cancer) : Two weeks regimen : Dirozyl??(Metronidazole) 500 mg thrice daily plus Moxilin (Amoxycillin) 750 mg thrice daily plus Ranidin (Ranitidine) 300 mg at night or 150 mg twice daily. \n \n