\n \nCalcitriol BP \n \nComposition :?Calcitriol 0.25mcg Soft Capsule. \n \nIndication :?Predialysis patients : Dicaltrol is indicated in the management of secondary hyperparathyroidism and resultant metabolic bone disease in patients with moderate to severe chronic renal failure not yet on dialysis. Dialysis patients : Dicaltrol is indicated in the management of hypocalcaemia and the resultant metabolic bone disease in patients undergoing chronic renal dialysis. Hypoparathyroidism patients : Dicaltrol is also indicated in the management of hypocalcaemia and its clinical manifestations in patients with post surgical hypoparathyroidism, idiopathic hypoparathyroidism and pseudohypoparathyroidism. Osteoporosis : Dicaltrol is also indicated for the treatment of established postmenopausal osteoporosis and senile osteoporosis. \n \nDosage and administration :?Predialysis Patients : The recommended initial dosage of Dicaltrol is 0.25 mcg/day in adults and pediatric patients 3 years of age and older. This dosage may be increased if necessary to 0.5 mcg/day. \n \nDialysis Patients : The recommended initial dose of Dicaltrol is 0.25 mcg/day. If a satisfactory response in the biochemical parameters and clinical manifestations of the disease state is not observed, dosage may be increased by 0.25 mcg/day at 4 to 8- week intervals. Hypoparathyroidism : The recommended initial dosage of Dicaltrol is 0.25 mcg/day given in the morning. If a satisfactory response in the biochemical parameters and clinical manifestations of the disease is not observed, the dose may be increased at 2 to 4 week intervals. if hypercalcaemia is noted, Dicaltrol should be immediately discontinued until normocalceamia ensues. Careful consideration should also be given to lowering the dietary calcium intake. Most adult patients and pediatric patients age 6 years and older have responded to dosages in the range of 0.5 mcg to 2 mcg daily. Pediatric patients in the 1 to 5 year age group with hypoparathyroidism have usually been given 0.25mcg to 0.75mcg daily. The number of treated patients with pseudohypoparathyroidism less than 6 years of age is too small to make dosage recommendations. \n \nPostmenopausal Osteoporosis : The recommended dose for Dicaltrol is 0.25 mcg twice daily. Serum calcium and creatinine levels should be determined at 4 weeks, 3 and 6 months and at 6 monthly intervals there after. \n \nUse in pregnancy and lactation :?Dicaltrol should be given only when the potential benefit has been weighed against the possible hazard to the fetus. Mothers should not breast-feed while taking Dicaltrol. \n \nPacking :?Dicaltrol : 5 x 10's capsule. \n \n